The Simpsons Cartoon Studio? “What the hell is this?!”, you may ask.
Cartoon Studio came out back in 1996 as yet another installment in
the long and mediocre Simpsons game franchise.

I should mention that I coin the term ‘game’ loosely when it comes
to Cartoon Studio. This is more like a cartoon creator. You are
given various cartoon elements like characters, backgrounds, props,
and sounds to create your own custom Simpsons cartoons.

So yea, take that FOX! I can make my own Simpsons cartoons! Well, I
did pay for this game, and they got some of that money…
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Creating your own Simpsons episodes is no longer a matter of fantasy — or waiting until you’ve gotten your degree from Harvard so you can join the show’s writing staff. No, now you can make slick-looking animation on your personal computer (Macintosh or Windows) using “The Simpsons Cartoon Studio.” With a few clicks of the mouse, you can add, rearrange and remove elements, including music and sound effects. The software also includes more than 10,000 cels of hand-drawn character animation. When you’re finished, you can save your Simpsons cartoon short and send it to friends, even if they don’t have the “The Simpsons Cartoon Studio” installed.

Found on Forums,
this game may be a bit old (it is from 1996 as far as I found out), but I am sure someone might find a use for it.
I used to own “Virtual Springfield” a few years ago (or was it ten?) and it owned.

You may also want to checkout this guide to get started at the game.

Simpsons Tetris Game

Also old like crap, but still fun and a laugh playing.
I could not test it, since I run Vista and it did not work on Vista. It is from 2002, so maybe too elite to work on my hypermodern setup, yiks..
For those of you who want to try anyway, find the link here (20kb, seriously)